Adaptogens Explained: What Science Says About Ashwagandha & Friends

Stress is a constant companion in modern life. Deadlines, notifications, sleepless nights—it all adds up. But what if nature offered a gentle ally to help our bodies handle stress better? That’s where adaptogens come in. Long rooted in traditional medicine, these herbs and botanicals are gaining popularity again. But what does science really say about them?

Let’s unpack the facts, the folklore, and how to approach them with intention.

What Are Adaptogens?

Adaptogens are a group of natural substances—mostly herbs and roots—that are thought to help the body "adapt" to stress. The term was first coined in the 1940s by Soviet scientists looking for ways to boost resilience in soldiers and workers. Since then, the list has grown to include plants from Ayurveda, Traditional Chinese Medicine (TCM), and other ancient systems.

While definitions vary slightly, most experts agree: adaptogens help balance the body’s systems, especially related to stress, energy, and immune response.

What Makes a Substance an Adaptogen?

To be classified as an adaptogen, a substance typically must:

  • Be non-toxic in normal doses

  • Help the body resist physical, chemical, or biological stress

  • Support overall balance, or "homeostasis," without overstimulating

In simpler terms, adaptogens don’t force a specific effect—they nudge the body toward balance. Kind of like a thermostat for your internal systems.

Meet the Most Popular Adaptogens

Here’s a look at a few adaptogens that have made their way from traditional medicine cabinets to modern-day supplements and wellness teas.

1. Ashwagandha (Withania somnifera)

Tradition: Used in Ayurvedic medicine for thousands of years.

Claim to Fame: Calms the nervous system, may reduce anxiety and cortisol.

What Science Says: Some studies suggest ashwagandha can lower stress hormones and support better sleep. It’s also being researched for its role in thyroid health and physical endurance.

Best for: High-stress lifestyles, chronic fatigue, or an overwhelmed nervous system

2. Rhodiola rosea

Tradition: Used in Russia, Scandinavia, and TCM

Claim to Fame: Boosts energy and improves mental focus

What Science Says: Small studies show promise for fighting fatigue, improving concentration, and even easing symptoms of depression—especially in high-stress settings.

Best for: Burnout recovery, brain fog, or mentally demanding jobs

3. Holy Basil (Tulsi)

Tradition: Sacred in India, with spiritual and medicinal uses

Claim to Fame: Balances mood and supports immunity

What Science Says: Tulsi is linked with reduced stress markers and improved respiratory and metabolic function. It also has mild antimicrobial properties.

Best for: Anxious minds, seasonal immunity, daily calming rituals

4. Eleuthero (Siberian Ginseng)

Tradition: Used in Eastern Europe and Asia.

Claim to Fame: Increases stamina and physical resilience.

What Science Says: Research shows it may improve exercise performance and help the body bounce back after physical stress.

Best for: Athletes, active lifestyles, or people recovering from illness

5. Maca Root

Tradition: Grown in the Andes and used for energy and fertility

Claim to Fame: Supports hormonal balance and vitality

What Science Says: Evidence is mixed, but some studies show it can support libido and energy, especially during perimenopause or hormonal shifts.

Best for: Hormonal changes, low libido, or reproductive wellness

Transitioning from Curiosity to Caution

Adaptogens sound magical, but they’re not one-size-fits-all. And while they’re natural, they’re still bioactive compounds—meaning they can affect you deeply.

Before trying any adaptogen, consider:

  • Your unique needs: Do you need calming or energizing?

  • Medication interactions: Always consult a healthcare provider if you’re on medication or have a health condition

  • Dosage and sourcing: Choose high-quality, lab-tested brands and start with low doses

Remember: adaptogens are helpers, not fixes. They support wellness, but don’t replace rest, sleep, nutrition, or therapy.

Image Credit: FotoHelin/Shutterstock.com

Do Adaptogens Really Work?

Here’s the tricky part—scientific research is still catching up. While some adaptogens like ashwagandha and rhodiola have more clinical data, others rely heavily on centuries of traditional use. Most studies are small, short-term, or not well-controlled.

That said, many users swear by them—and science is increasingly interested. In the coming years, we’ll likely see more evidence to support what ancient medicine has long practiced.

How to Start Using Adaptogens

Here’s a gentle way to dip your toes in:

  • Choose one adaptogen based on your needs

  • Try it in tea, tincture, or capsule form—whatever fits your lifestyle

  • Track how you feel over a few weeks (energy, mood, sleep, etc.)

  • Avoid mixing too many at once, especially if new to supplements

Listen to your body. Adaptogens are slow-builders, not quick fixes.

Final Thoughts

Adaptogens offer a beautiful intersection of ancient wisdom and modern wellness. Whether you’re trying to soften stress, regain energy, or simply feel more grounded, plants like ashwagandha and tulsi might offer quiet support.

But as with all things wellness, it’s not about trends—it’s about tuning in. If something supports your balance and helps you feel more like yourself, that’s a practice worth keeping.

Marin Cole, RD

Marin is a registered dietitian and food blogger who makes clean eating approachable and delicious. Her content combines nutrition science with easy-to-follow recipes and real-life eating tips.